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Gene Expression Literature Summary
Assay
Age
In situ RNA (section)
15.5 DPC

11 matching records from 11 references.

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Neurog3  neurogenin 3   (Synonyms: Atoh5, bHLHa7, Math4B, ngn3)
Results  Reference
1J:156022 Anderson KR, White P, Kaestner KH, Sussel L, Identification of known and novel pancreas genes expressed downstream of Nkx2.2 during development. BMC Dev Biol. 2009;9:65
1J:57072 Apelqvist A, Li H, Sommer L, Beatus P, Anderson DJ, Honjo T, Hrabe de Angelis M, Lendahl U, Edlund H, Notch signalling controls pancreatic cell differentiation. Nature. 1999 Aug 26;400(6747):877-81
1J:60642 Gradwohl G, Dierich A, LeMeur M, Guillemot F, neurogenin3 is required for the development of the four endocrine cell lineages of the pancreas. Proc Natl Acad Sci U S A. 2000 Feb 15;97(4):1607-11
1J:94455 Harmon EB, Apelqvist AA, Smart NG, Gu X, Osborne DH, Kim SK, GDF11 modulates NGN3+ islet progenitor cell number and promotes {beta}-cell differentiation in pancreas development. Development. 2004 Dec;131(24):6163-6174
1J:80672 Jenny M, Uhl C, Roche C, Duluc I, Guillermin V, Guillemot F, Jensen J, Kedinger M, Gradwohl G, Neurogenin3 is differentially required for endocrine cell fate specification in the intestinal and gastric epithelium. EMBO J. 2002 Dec 2;21(23):6338-47
1J:120581 Jensen J, Heller RS, Funder-Nielsen T, Pedersen EE, Lindsell C, Weinmaster G, Madsen OD, Serup P, Independent development of pancreatic alpha- and beta-cells from neurogenin3-expressing precursors: a role for the notch pathway in repression of premature differentiation. Diabetes. 2000 Feb;49(2):163-76
1J:219263 Paul V, Tonchev AB, Henningfeld KA, Pavlakis E, Rust B, Pieler T, Stoykova A, Scratch2 modulates neurogenesis and cell migration through antagonism of bHLH proteins in the developing neocortex. Cereb Cortex. 2014 Mar;24(3):754-72
1J:168022 Pelling M, Anthwal N, McNay D, Gradwohl G, Leiter AB, Guillemot F, Ang SL, Differential requirements for neurogenin 3 in the development of POMC and NPY neurons in the hypothalamus. Dev Biol. 2011 Jan 15;349(2):406-16
1*J:63215 Schwitzgebel VM, Scheel DW, Conners JR, Kalamaras J, Lee JE, Anderson DJ, Sussel L, Johnson JD, German MS, Expression of neurogenin3 reveals an islet cell precursor population in the pancreas. Development. 2000 Aug;127(16):3533-42
1*J:215487 Thompson CL, Ng L, Menon V, Martinez S, Lee CK, Glattfelder K, Sunkin SM, Henry A, Lau C, Dang C, Garcia-Lopez R, Martinez-Ferre A, Pombero A, Rubenstein JL, Wakeman WB, Hohmann J, Dee N, Sodt AJ, Young R, Smith K, Nguyen TN, Kidney J, Kuan L, Jeromin A,Kaykas A, Miller J, Page D, Orta G, Bernard A, Riley Z, Smith S, Wohnoutka P, Hawrylycz MJ, Puelles L, Jones AR, A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain. Neuron. 2014 Jul 16;83(2):309-23
1J:183127 Westmoreland JJ, Kilic G, Sartain C, Sirma S, Blain J, Rehg J, Harvey N, Sosa-Pineda B, Pancreas-specific deletion of prox1 affects development and disrupts homeostasis of the exocrine pancreas. Gastroenterology. 2012 Apr;142(4):999-1009.e6

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory